JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2,JARID1C,JMJD1A,JMJD1B,JMJD1C,JMJD2A,JMJD2C and JMJD2D. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism.
应用类型
Western blotting (1 - 4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects JMJ1DC of human origin. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 1003 of human JMJD1C