Bax is a Bcl-2 family pro-apoptotic protein. Bax promotes cell death by forming homodimers,which can be blocked by forming heterodimers with Bcl-2 or Bcl-XL. Bax has three different isoforms,which are Bax-,B,and g. The 21 kDa Bax- is the most common form in most of the cells and tissues.
应用类型
Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects the 21 kDa Bax in samples of human, mouse, and rat origins.
免疫原
Synthetic peptide surrounding amino acids 15 of human Bax.
来源宿主
小鼠
反应性
经检测验证,可与人、小鼠、大鼠种属来源的Bax蛋白发生免疫反应.
保存建议
提供的Bax抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该Bax抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.