Death Associated Protein 1 （DAP1） is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-gamma. The DAP1 protein is praline-rich and possesses one SH3 binding motif，as well as several consensus protein kinase phosphorylation sites. The protein is localized in the cytoplasma，however the detailed mechanism of its proapoptotic function is unclear.
应用类型
Western blotting （0.5-4 ug/ml） in samples from human， mouse and rat origins. However， the optimal conditions should be determined individually. The antibody detects the 25 kDa large subunit of caspase-8. It does not detect the full-length of caspase-8.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 96 of human DAP1.
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的DAP1蛋白发生免疫反应
保存建议
提供的100 ug DAP1抗体产品为无色溶液其浓度为0.2 mg/ml溶解于包含有50%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该DAP1抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
