Enhancer of zeste homolog 2 （Ezh2） is a member of the Polycomb group （PcG）. The PcG proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity，cell cycle regulation，and oncogenesis. Enhancer of zeste homolog 2 （Ezh2） contains four conserved regions including domain I，domain II，and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. Ezh2 also plays a role as primary effector and as a mediator of tumorigenesis.
应用类型
Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3242BP-50） is available separately.
免疫原
Synthetic peptide mapping to the N-terminus of rat Ezh2
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的EZH2蛋白发生免疫反应
保存建议
提供的100 ug EZH2抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该EZH2抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
