The MBD family of proteins includes MeCP2，MBD1，MBD2，MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms，MBD2a and MBD2b. MBD2a is a 414 amino acids protein，whereas MBD2b lacks the 152 amino acids N-terminal extension. MBD2a interacts with RNA helicase A to enhance CREB-dependent gene exptression.
应用类型
The antibody can be used in Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3232BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 164 of rat MBD2a
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的MBD2a蛋白发生免疫反应
保存建议
提供的100 ug MBD2a抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该MBD2a抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
