NAIP （neuronal apoptosis inhibitor protein） is a member of the IAPs （inhibitor of apoptosis proteins） that function in cell death pathways to inhibit apoptosis. NAIP was discovered based on its association with a neurodegenerative disorder. Mutations and deletions in the NAIP gene locus is a contributing factor in spinal muscular atrophy. Coexpression of NAIP and hippocalcin protects neurons against calcium-induced cell death. NAIP is strongly expressed in anterior horn and motor cortex neurons of the normal brain. It is also found in human fetal neurons and in adult choroid plexus cells.
应用类型
The antibody detects recombinant human NAIP in extracts from Sf21 insect cells by Western blot analysis （0.5-4 ug/ml）.
免疫原
Synthetic peptide surrounding amino acid 506 of human NAIP
来源宿主
兔
反应性
经检测验证，可与人种属来源的NAIP蛋白发生免疫反应.
保存建议
提供的NAIP抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该NAIP抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
