Silent information regulator （Sir2）-like family deacetylases （also known as sirtuins） are highly conserved proteins and have important roles in the regulation of metabolism，inflammation，cellular survival growth and differentiation. SIRT3 is a member of the sirtuin family of proteins，homologs to the yeast Sir2 protein. Yeast sirtuin proteins are found to regulate epigenetic gene silencing. Sirtuins are NAD-dependent protein ADP-ribosyl transferase which catalyzes the transfer of ADP-ribosyl groups onto target proteins.
应用类型
Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3223BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 387 of human SIRT3
来源宿主
兔
反应性
经检测验证，可与人种属来源的SIRT3蛋白发生免疫反应
保存建议
提供的100 ug SIRT3抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该SIRT3抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
