BAFF （for B cell Activating Factor） is a novel member in the TNF family. BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNF- and TRAIL，THANK was shown to activate NF-kB and c-Jun N-terminal kinase （JNK） and to induce apoptosis.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. A 32 kDa full length BAFF and the 18 kDa cleavage fragment can be detected.
免疫原
Recombinant human BAFF
来源宿主
兔
反应性
经检测验证，可与人种属来源的BAFF蛋白发生免疫反应.
保存建议
提供的BAFF抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该BAFF抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
