The precursor of cytochrome c，apocytochrome c，is synthesized in the cytoplasm. Upon translocation into mitochondria，cytochrome c acquires a heme moiety required for functionality in the mitochondrial respiration chain. The heme-bound form of cytochrome c is called holocytochrome c. When released into the cytosol，cytochrome c can activate caspases responsible for apoptosis.
应用类型
Western blot analysis （5-10 ug/ml） and immunoprecipitation. The antibody detects a 12.0 kDa protein corresponding to the apparent molecular weight of cytochrome c.
免疫原
Cytochrome c purified from human heart
来源宿主
小鼠
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Holocytochrome c蛋白发生免疫反应.
保存建议
提供的Holocytochrome c抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02% 叠氮钠的PBS缓冲液中.请将该Holocytochrome c抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
