Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers，but undetectable in terminally differentiated adult tissues. It has been shown that recombinant expression of Survivin counteracts apoptosis of B lymphocyte precursors deprived of interleukin 3 （IL-3），suggesting a potential role of Survivin in cancer therapy. Survivin is expressed in G2-M phase in a cell cycle-dependent manner and directly associated with mitotic spindle microtubules，suggesting a role in both apoptosis regulation and cell cycle progression.
应用类型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
Recombinant human survivin
来源宿主
兔
反应性
经检测验证，可与人种属来源的Survivin蛋白发生免疫反应
保存建议
提供的100 ug Survivin抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Survivin抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
