SOX4 is a member of the SOX （SRY-related HMG-box） family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins，such as syndecan binding protein （syntenin）. The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone （PTH） and PTH-related protein （PTHrP） in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
应用类型
The antibody can be used for ELISA （0.25 ug/ml） and Western Blotting （2.5 – 5.0 ug/ml）.
免疫原
Synthetic peptide selected from the N-terminal region of human SOX4
来源宿主
兔
反应性
经检测验证，可与人种属来源的SOX4蛋白发生免疫反应.
保存建议
提供的SOX4抗体产品为100 ug 无色溶液，其浓度为0.25 mg/ml，溶解于包含有0.09% （W/V） 叠氮钠的PBS缓冲液中.请将该SOX4抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
