Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by upstream caspases to form active caspase-7 in apoptosis. Once activated，caspase-7 cleaves many of the same substrates as caspase-3，including poly (ADP-ribose) polymerase (PARP) and sterol regulatory element binding proteins (SREBPs).
应用类型
Western blot
免疫原
Synthetic peptide corresponding to residues surrounding the cleavage site of human caspase-7 large fragment
