MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10，also known as EGAP，is one subunit of a novel N-terminal acetyltransferase （NAT） that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult，remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development.
应用类型
Western blotting （2-4 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 201 of rat MAK10
来源宿主
兔
反应性
经检测验证，可与人、大鼠种属来源的MAK10蛋白发生免疫反应
保存建议
提供的100 ug MAK10抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该MAK10抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
