Proinsulin is a prohormone precursor to Insulin，made by the pancreas in response to increased blood sugar. Proinsulin is 39 amino acids longer than the mature Insulin，of which 4 are completely lost and the remaining 35 forms the C-peptide. The measurement of Proinsulin in serum provides a useful，valuable information for the diagnosis of insulinomas. Proinsulin levels have also been shown to be elevated in non-insulin dependent diabetics （NIDDM），in insulin dependent diabetics （IDDM） and other clinical situations. The antibody recognizes insulin and recombinant proinsulin，but does not react with synthetic C-peptide.
应用类型
The antibody can be used for indirect ELISA， WB and IHC.
免疫原
Recombinant full length insulin
来源宿主
小鼠
反应性
经检测验证，可与人、牛、猪种属来源的ProInsulin蛋白发生免疫反应.
保存建议
提供的ProInsulin抗体产品为100 ug 无色溶液，其浓度为1.0 mg/ml，溶解于包含有0.05% （W/V） 叠氮钠的PBS缓冲液中.请将该ProInsulin抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
