TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development，TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. At later stages in development，TCTN1 is thoμght to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 520 of rat TCTN1
