TCTN1 belongs to the Tectonic protein family that regulate Hedgehog （Hh） pathway. During neural tube development，TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. At later stages in development，TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
应用类型
Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3088BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 520 of rat TCTN1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TCTN1蛋白发生免疫反应
保存建议
提供的100 ug TCTN1抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该TCTN1抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
