c-FLIP was cloned by several labs independently and termed Casper，I-FLICE，FLAME-1，CASH AND CLARP. c-FLIP contains two death effector domains and has sequence homology to caspase-8. c-FLIP interacts with adapter protein FADD and caspaser-8 and -10，and potently inhibits apoptosis induced by all known death receptors. Two splice variants of c-FLIP have been identified and termed FLIPl and FLIPs
应用类型
Western blot, Immunofluorescence
免疫原
Synthetic peptide near the C-terminus of human FLIPa/FLIPL form
