Caspase-9 is one of the most important caspases among the caspase family members. Caspase-9 is synthesized as inactive pro-enzyme that is processed in cells undergoing apoptosis. The processed caspase-9 consists of large (32-35 kD) and small (10 kD) subunits which associate to form an active enzyme. Activated caspase-9 in turn cleaves and activates caspase-3，one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 290 of human caspase-9
