Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Synonyms:DBCO-PEG4-succinimidyl ester; DBCO-PEG4-NHS ester; DBCO-PEG4-SEMDL No:MFCD26793797Molecular Formula:C34H39N3O10Molecular Weight:649.69Appearance:Supplied as a white to yellow oilPurity:≥96%Applications: Suitable for use in protein-peptide conjugates, antibody-enzyme or antibody-drug conjugates, protein or peptide-oligonucleotide conjugates and surface modification.Storage and Stability:May be stored at -20°C. Stable for 6 months after receipt at -20°C.Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
