A phospholipid drug with antineoplastic and antiprotozoal/antifungal properties, also acts as an Akt inhibitor, and under investigation as a potential therapy against HIV infection. Used for the treatment of visceral and cutaneous leishmaniasis. Active against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis.1 HePC induces an apoptosis-like cell death in the unicellular protozoan parasite Leishmania donovani, the causative agent of leishmaniasis.Hexadecylphosphocholine (HePC) is an effective apoptosis inducer. Originally developed as an anticancer drug and has been used for treatment of skin metastases of breast cancer. The anti-tumor activity of HePC has been linked with its capacity to induce apoptosis in numerous tumor cell lines. Due to its amphiphilic behavior, HePC accumulates at the cell membrane, affecting membrane fluidity and triggering the apoptotic cell death. Appearance: White to off-white powderPurity: ≥98%Identity (IR): Conforms to structureSolubility (H2O): Soluble to 10mg/ml, clear, colorlessStorage and Stability:Powder may be stored at 4°C. Stable for 6 months after receipt.
