SPDP交联剂(50 mg)产品是KEY FEATURES:n• SPDP contains a dithiopyridyl group which is reactive towards cysteines (-SH groups) and an NHS group, which is useful when targeting primary amines (-NH2 groups)n• SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343 nm, the reaction can be easily followedn• Contains a disulfide linkage in its spacer arm with a length of 6.8 Ån• The spacer is cleavable with reducing agent, such as DTT, TCEP, etc.nAPPLICATIONS:n• Reversible crosslinking of proteinsn• N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines, as found in lysine side chainsn• Useful for adding sulfhydryl groups to proteins by attachment to lysine residuesn• Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates