D-dimer is formed as a result of thrombin activation, clot formation and subsequent clot lysis. The presence of fibrin degradation products in blood samples is an indicator of various coagulation disorders, including deep vein thrombosis. Source:Human plasmaStorage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.