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中文名称

Beta-Lactamase Inhibitor Screening BioAssay Kit, Colorimetric (BetaL)

英文名字
Beta-Lactamase Inhibitor Screening BioAssay Kit, Colorimetric (BetaL)
供应商
USBiological
产品货号
219462
产品报价
¥1/100Tests
产品说明书
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产品新闻
背景资料
USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
产品描述
Beta-Lactamase (betaL), (EC 3.5.2.6), is a bacterial enzyme that hydrolyzes the beta-Lactam ring, a four-carbon ring, the building block of beta-Lactam antibiotics. beta-Lactams inhibit transpeptidases, enzymes that participate in the biosynthesis of bacterial cell walls. Penams, Carbapenems, Cephems, Clavams, Oxacephems and Monobactams have been widely used for the treatment of bacterial infections since the discovery of penicillin, the first beta-Lactam antibiotic, and its bactericidal effect more than eighty years ago. However, an alarming number of cases of beta-Lactam antibiotic-resistant infections have been reported. The resistance is found in bacterial strains producing beta-Lactamase, which is responsible for diminishing the beta-Lactam antibiotic potency. beta-Lactamase inhibition, therefore, has become an urgent target in the treatment of bacterial infections displaying beta-Lactam resistance. Several beta-Lactam derivatives have been reported as beta-Lactamase inhibitors; however, only clavulanic acid, sulbactam and tazobactam have reached clinical importance. Intended Use:For use in screening, studying and characterizing beta-Lactamase Inhibitors for efficient treatment of antibiotic resistant bacterial infections.Test Principle:The beta-Lactamase Inhibitor Screening Kit utilizes the ability of the enzyme to hydrolyze Nitrocefin, a well-known beta-Lactamase substrate. In the presence of Clavulanic Acid-a potent inhibitor of beta-Lactamase, the rate of hydrolysis of the substrate is decreased. The kit provides a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of beta-Lactamase inhibitors.Kit Components:beta-Lactamase Assay Buffer, 1x25ml
Nitrocefin, in DMSO, 1x0.1ml
beta-Lactamase, lyophilized, 1x vial
Inhibitor Control (Clavulanic Acid), 1x vialStorage and Stability:Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
产品特点
针对Beta-Lactamase Inhibitor Screening BioAssay Kit, Colorimetric (BetaL)该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Beta-Lactamase Inhibitor Screening BioAssay Kit, Colorimetric (BetaL)产品后将其置于-20°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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