中文名称

Salinomycin, Sodium Salt

英文名字

Salinomycin, Sodium Salt

供应商

USBiological

产品货号

217883

产品报价

￥1/5mg   ￥1/10mg   ￥1/50mg

产品说明书

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购买方式

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产品新闻

背景资料

USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述

Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within HMLER breast cancer cells (IC50s = ~24 versus ~90uM).1 At 8uM, salinomycin treatment of 4T1 and MCF7Ras breast cancer cell lines results in a ~2-fold and ~3-fold, respective reduction of CSCs relative to controls.1 Treatment of 5mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells.Solubility:Salinomycin (sodium salt) is supplied as a crystalline solid. A stock solution may be made by dissolving the salinomycin (sodium salt) in the solvent of choice. Salinomycin (sodium salt) is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of salinomycin (sodium salt) in these solvents is approximately 10, 5, and 20mg/ml, respectively.Salinomycin (sodium salt) is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, salinomycin (sodium salt) should first be dissolved in DMF and then diluted with the aqueous buffer of choice. Salinomycin (sodium salt) has a solubility of approximately 0.2 mg/ml in a 1:4 solution of DMF:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive.

产品形式

该产品为晶状固体。

保存建议

接收到Salinomycin, Sodium Salt产品后，置于-20°C温度下保存。

其他

Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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