A highly potent, selective positive allosteric modulator for mGlu receptor subtype 4 (EC50 = 0.8 and 0.7uM at human and rat mGlu4 receptors respectively). Does not interact with other mGluR subtypes. Significant antiparkinsonian effects in two preclinical rodent models of Parkinson's disease when administered intracerebroventricularlly (icv).Formula:C14H14Cl2NNaO3Solubility:H2OStorage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
产品形式
该产品为白色固体。
保存建议
接收到VU0155041, Sodium Salt (cis-2-(3,5-Dichlorophenylcarbamoyl)cyclohexanecarboxylic Acid Sodium Salt)产品后，置于4°C温度下保存。
