SKP2 E3 Ligase Inhibitor II, SMIP004 (CRL1SKP2 Inhibitor II, p21/Cip1/CKI/Waf1 Activator II, N-(4-Butyl-2-methylphenyl)acetamide, p27/Kip1 Activator II, S-phase Kinase-associated Protein 2 Inhibitor I-SKP2 E3 Ligase Inhibitor II, SMIP004 (CRL1SKP2 Inhibitor II, p21/Cip1/CKI/Waf1 Activator II, N-(4-Butyl-2-methylphenyl)acetamide, p27/Kip1 Activator II, S-phase Kinase-associated Protein 2 Inhibitor II, SCFSKP2 Inhibitor II, Small Molecule Inhibitor代理/参数/厂家-生化试剂-艾美捷科技有限公司

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中文名称: SKP2 E3 Ligase Inhibitor II, SMIP004 (CRL1SKP2 Inhibitor II, p21/Cip1/CKI/Waf1 Activator II, N-(4-Butyl-2-methylphenyl)acetamide, p27/Kip1 Activator II, S-phase Kinase-associated Protein 2 Inhibitor I

英文名字: SKP2 E3 Ligase Inhibitor II, SMIP004 (CRL1SKP2 Inhibitor II, p21/Cip1/CKI/Waf1 Activator II, N-(4-Butyl-2-methylphenyl)acetamide, p27/Kip1 Activator II, S-phase Kinase-associated Protein 2 Inhibitor II, SCFSKP2 Inhibitor II, Small Molecule Inhibitor

背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: A cell-permeable phenylacetamide compound that is shown to upregulate p21Cip1/Waf1 and/or p27Kip1 in prostate cancer LNCaP, PC3, DU145, but not HeLa, cultures (40uM for 24h) with a concomitant downregulation of the F-box E3 ubiquitin ligase Skp2 and a delayed G1-to-S cell cycle transition, displaying no apparent effect toward cell cycle progression or p21 and p27 levels in non-cancer human fibroblast IMR90. SMIP004 antiproliferative activity against LNCaP, PC3, DU145 soft agar colony formation is mainly cytostatic with cytotoxicity observed only in LNCaP cultures at high concentrations (IC50 = 40uM in 72h), but not PC3 or DU145 even at concentrations as high as 80uM and for up to 96h. Solubility:DMSOMolar Mass:205.30Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

保存建议: 接收到SKP2 E3 Ligase Inhibitor II, SMIP004 (CRL1SKP2 Inhibitor II, p21/Cip1/CKI/Waf1 Activator II, N-(4-Butyl-2-methylphenyl)acetamide, p27/Kip1 Activator II, S-phase Kinase-associated Protein 2 Inhibitor II, SCFSKP2 Inhibitor II, Small Molecule Inhibitor of p27 Depletion 004)产品后，置于4°C温度下保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。