Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 (2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic Acid, CDC42 Inhibitor I, CID1067700, Cdc42 GTPase-Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 (2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic Acid, CDC42 Inhibitor I, CID1067700, Cdc42 GTPase Inhibitor I, H-Ras GTPase Inhibitor, Rab GTPase I代理/参数/厂家-生化试剂-艾美捷科技有限公司

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中文名称: Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 (2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic Acid, CDC42 Inhibitor I, CID1067700, Cdc42 GTPase

英文名字: Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 (2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic Acid, CDC42 Inhibitor I, CID1067700, Cdc42 GTPase Inhibitor I, H-Ras GTPase Inhibitor, Rab GTPase I

背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: A thiourea-derived small molecule that acts as a competitive inhibitor of nucleotide (BODIPY-GTP and BODIPY-GDP) binding by Rab7 (Ki=12.89-19.70nM). Equilibrates rapidly with Rab7 without affecting the rate of release of bound BODIPY-GTP or BODIPY-GDP. However, it exhibits a slightly lower potency against BODIPY-GDP bound Rab7 than BODIPY-GTP bound Rab7A. Acts by binding to the nucleotide binding pocket of Rab7. Also shown to inhibit nucleotide binding by mutant forms of Rab7 (Rab7Q67L and Rab7T22N) that are constitutively in the GTP and GDP bound states, with good potency. Also shown to block the nucleotide binding of several other Ras-related GTPases, but with reduced potency.Formula:C18H18N2O4S2Primary Target:Rab7Primary Target Ki:12.89-19.70nMSolubility:DMSOMolecular Weight:390.5Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

保存建议: 接收到Ras Superfamily GTPases GTP/GDP Binding Antagonist, CID 1067700 (2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic Acid, CDC42 Inhibitor I, CID1067700, Cdc42 GTPase Inhibitor I, H-Ras GTPase Inhibitor, Rab GTPase Inhibitor, Rab2 GTPase Inhibitor, Rab7 GTPase Inhibitor, Rac1 GTPase Inhibitor, Rac1 InhibitorIV)产品后，置于4°C温度下保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。