A potent antagonist selective for mGlu1a receptors (IC50 = 8.8uM and >100uM for mGlu1a and mGlu5a, respectively). Negligible effect on group II and III mGlu receptors. Frequently used in studies assessing the functional roles of mGlu1a in various brain functions and disorders in which neural transmissions via mGlu1a receptors are involved.Formula:C10H11NO4Å•HClSolubility:H2OPrimary Target:mGlu1 receptorsPrimary Target IC50:8.8uMStorage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.