L3MBTL3 MBT Domain Blocker, UNC1215 (Lethal(3)malignant Brain Tumor-like Protein 3 MBT Domain Blocker, 2-Phenylamino-1,4-bis(4-(pyrrolidinyl)piperidinyl)benzamide, TFA, 2-(Phenylamino)-1,4-phenylene-b-L3MBTL3 MBT Domain Blocker, UNC1215 (Lethal(3)malignant Brain Tumor-like Protein 3 MBT Domain Blocker, 2-Phenylamino-1,4-bis(4-(pyrrolidinyl)piperidinyl)benzamide, TFA, 2-(Phenylamino)-1,4-phenylene-bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone, T代理/参数/厂家-生化试剂-艾美捷科技有限公司

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中文名称: L3MBTL3 MBT Domain Blocker, UNC1215 (Lethal(3)malignant Brain Tumor-like Protein 3 MBT Domain Blocker, 2-Phenylamino-1,4-bis(4-(pyrrolidinyl)piperidinyl)benzamide, TFA, 2-(Phenylamino)-1,4-phenylene-b

英文名字: L3MBTL3 MBT Domain Blocker, UNC1215 (Lethal(3)malignant Brain Tumor-like Protein 3 MBT Domain Blocker, 2-Phenylamino-1,4-bis(4-(pyrrolidinyl)piperidinyl)benzamide, TFA, 2-(Phenylamino)-1,4-phenylene-bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone, T

背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: A cell-permeable pyrrolidinyl-piperidinyl-benzamide that effectively competes against H4K20Me2 peptide for L3MBTL3 binding by targeting the first two L3MBTL3 MBT domains (Kd = 120nM in binding studies using recombinant 3MBT fragment), while exhibiting much reduced potency against L3MBTL1-H4K20Me1, 53BP1-H4K20Me2, MBTD1-H4K20Me1, or L3MBTL4-H2AK36Me1 interaction (IC50 ≥2uM; [peptide] = 150nM). Shown to increase GFP-L3MBTL fusion nucleus mobility (10nM to 1uM) in HEK293 transfectants. X-ray structural analysis reveals two 3MBT are bridged together by two UNC1215 molecules in a reciprocal fashion. Solubility:DMSOPrimary Target:Kme binding ligand of L3MBTL3Primary Target IC50:40nMPrimary Target Ki:0.12uMolar Mass:529.7Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

保存建议: 接收到L3MBTL3 MBT Domain Blocker, UNC1215 (Lethal(3)malignant Brain Tumor-like Protein 3 MBT Domain Blocker, 2-Phenylamino-1,4-bis(4-(pyrrolidinyl)piperidinyl)benzamide, TFA, 2-(Phenylamino)-1,4-phenylene-bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone, TFA)产品后，置于-20°C温度下保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。