A non-selective inhibitor of dopamine and noradrenalin transporters (Ki = 1.4, 2.8 and 45uM for dopamine, noradrenalin, and serotonin transporters respectively). Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs) (IC50 = 1.8uM at alpha2beta2 receptor). Clinically used as an antidepressant and smoking seceasion drug. Used in nicotinic addiction and depression studies. Solubility:H2OPrimary Target:DAT/NETPrimary Target Ki:1.4uStorage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
产品形式
该产品为白色固体。
保存建议
接收到Bupropion Hydrochloride (Dopamine and Noradrenalin Transporter Inibitor, Bupropion)产品后,置于4°C温度下保存。