A selective positive allosteric modulator for mGlu receptor subtype 2 (EC50 = 33.2nM in CHO cells expressing human mGlu2). No effect on other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.Formula:C30H30O4Solubility:DMSOPrimary Target:mGlu2Molar Mass:454.56Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
