PLSCR1 (Phospholipid Scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.
应用类型
IP, WB, FC, ICC
免疫原
Pooled lipid raft fraction isolated from RBL-2H3 cells
来源宿主
小鼠
反应性
Rat
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.