Anti-Transferrin Antibody, Biotin Conjugated is specific for the transferrin protein. Transferrins are iron-binding blood plasma glycoproteins which regulate the level of free iron in biological fluids. When free of bound iron, transferrin is referred to as apotransferrin. Human transferrin is encoded by the TF gene and is mainly synthesized in the liver, but other sources, such as the brain produce it. The main role of transferrin is delivery of iron from absorption centers in the duodenum and macrophages to all tissues. Membrane receptors on erythroid precursors in the bone marrow avidly bind transferrin. Hereditary hemochromatosis and anemia are well establish disorders involving defects in transferrin transport defects. Anti-Transferrin Antibody, Biotin Conjugated is suitable for use in cardiovascular research as well as other basic research.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Transferrin [Human Serum]
来源宿主
Rabbit
反应性
H. sapiens (Human)
保存建议
Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
