DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In nFSHD individuals, the expression of the full-length DUX4 transcipt is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
应用类型
Immunohistochemistry,IF Microscopy,Western Blot,
免疫原
DUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein.
来源宿主
Mouse
反应性
H. sapiens (Human)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
