- 中文名称
Bovine Serum Albumin (BSA)
- 英文名字
- Bovine Serum Albumin (BSA)
- 供应商
- USBiological
- 产品货号
- 208761
- 产品报价
- ¥1/100mg

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
- 产品描述
- Albumin (Latin: albus, white) refers generally to any protein with water solubility and heat sensitive or heat coagulation (protein denaturation). Substances containing albumin, such as egg white, are called albuminoids. The most well-known type of albumin is the serum albumin in the blood. Serum albumin is the most abundant blood plasma protein and is produced in the liver and forms a large proportion of all plasma protein. In human, albumin may represent up to 50-60% plasma proteins. All other proteins present in blood plasma are referred to collectively as globulins. Low albumin (hypoalbuminaemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition, late pregnancy, artefact, posture, genetic variations and malignancy. High albumin may be either caused by dehydration or other factors. Albumin is synthesized in the liver as preproalbumin, which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to give the secreted protein. Albumin is a globular, non-glycosylated, soluble, monomeric protein (65kD) which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in the ALB gene on chromosome 4 result in various anomalous proteins. Albumin is negatively charged. The glomerular basement membrane is also negatively charged; this prevents the filtration of albumin in the urine. In nephrotic syndrome, this property is lost, and there is more albumin loss in the urine. Nephrotic syndrome patients are given albumin to replace the lost albumin. Human serum albumin (HSA) is widely used to stabilize blood volume. HAS is typically obtained from donors. However, there is concern about the transmission of many diseases such as HIV & Hepatitis. The use of recombinant HAS (rHSA) can be produced in vitro (E. coli or mammalian cells) and therefore has no diseases concerns. rHSA is identical to the natural blood. Recombinant Human HSA produced in mammalians is a single, glycosylated, polypeptide chain containing 585aa and having a molecular mass of ~66.441kD. Albumin performs many functions including maintaining the "osmotic pressure" that causes fluid to remain within the blood stream instead of leaking out into the tissues. Liver disease, kidney disease, and malnutrition are the major causes of low albumin. A diseased liver produces insufficient albumin. Diseased kidneys sometimes lose large amounts of albumin into the urine faster than the liver can produce it (this is termed nephrotic syndrome). Plasma albumin concentration is an important indicator of nutritional status, and low concentrations pre-surgery increase the risk of post-operative wound dehiscence, seroma formation and infection. Albumin levels are also dependant on the state of hydration of the body. A person that is dehydrated will have an artificially low albumin level. This returns to normal when the dehydration is corrected. Albumin fluctuates so widely because it is very sensitive to changes in hydration of the body. Albumin is also used as carrier protein for conjugating haptens (peptides, drugs, hormones, proteins etc) to make antibodies. It is also used as a model antigen along with ovalbumin, DNP, KLH etc. Albumin is commonly used as a carrier protein additives, buffer additives, or a general purpose blocking agent in ELISA, Western, and IHC applications.Biochemical Analysis:Protein: 100%Moisture: 0.60%Ash: 0.90%pH: 6.8Protease: Not detectedHeavy Metals: ≤0.025ppmBovine IgG: None Detected Bluetongue Virus: None Detected Vesicular Stomatitis virus: None Detected Applications: Suitable for use in ELISA and Western Blot. Other applications not tested.Recommended Dilutions:Optimal dilutions to be determined by the researcher.Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 产品形式
- 该产品为冻干粉形式。 No preservative added,缓冲液为:sterile PBS or TBS at 1-10%。
- 保存建议
- 接收到Bovine Serum Albumin (BSA)产品后,置于-20°C温度下保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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