Antibiotic. Bacterial DNA gyrase inhibitor: Staphylococcus aureus (IC50=1.45uM), E. coli (IC50=0.41uM). Human topoisomerase II (Topo II) inhibitor (IC50=100uM). Antibacterial (Gram-positive). Antitumor compound.Source:Streptomyces antibioticus Tü 6040Formula:C46H42ClNO18 Solubility:DMSO, methanol, acetone, dichloromethane or ethyl acetate.Molecular Weight:~932.3Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
