Antibiotic. Antitumor compound. Powerful, selective inhibitor of nucleic acid synthesis in vitro. Potent hypoxia-inducible factor 1 (HIF-1) DNA binding activity inhibitor. Apoptosis inducer. Antibacterial, antifungal and antiviral.Appearance:Supplied as a white to off-white solid.Purity:≥98% (HPLC)Source:Streptomyces echinatus (DSM 40013)Formula:C51H64N12O12S2 Solubility:Acetone, DMSO, methanol, dichloromethane or ethyl acetateMolecular Weight:~1101.3Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
