Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Autophagy inhibitor.Source:Streptomyces sp.Formula:C46H75NO14 Solubility:Soluble in methanol, DMSO or acetonitrile; insoluble in H2OMolecular Weight:~866.1Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
产品形式
该产品为白色或类白色固体。
保存建议
接收到Concanamycin A (High purity) (Olimycin, Antibiotic TAN 1323B, Antibiotic X4357B)产品后，置于-20°C温度下保存。
