- 中文名称
14,15-dehydro Leukotriene B4 (500 ug)
- 英文名字
- 14,15-dehydro LTB4, 14,15-dehydro Leukotriene B4, 5S,12R-dihydroxy-6Z,8E,1E-eicosatrien-14-ynoic acid
- 供应商
- Cayman
- 产品货号
- 20150-500
- 产品报价
- ￥23968/500 ug
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 uM.
- 产品描述
- A LTB4 receptor antagonist that has a higher binding affinity for BLT1 (Ki = 27 nM) compared to BLT2 (Ki = 473 nM); inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 uM
- 产品形式
- 保存建议
- -80
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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