QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be downregulated in the brain of schizophrenic patients. Anti-QKI (pan) is ideal for research in Neuroscience and Gene Expression.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Anti-QKI (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-341 (full length) of human QKI-5.
来源宿主
Mouse
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.