The spliceosome associated protein of 49 kDa (SAP49), also known as SF3B4, is a widely expressed nuclear splicing factor that has been shown to have RNA binding activity as well as direct interaction with SAP145. The SAP145-SAP49 complex has recently been implicated in cell cycle progression as Vpr (viral protein 1 of HIV-1) has been shown to bind SAP145 thus interfering with the proper formation and functioning of the SAP145-SAP49 complex. SAP 49 Antibody is ideal for researchers interested in cell cycle research.
应用类型
ELISA,IF Microscopy,Western Blot,
免疫原
Anti-SAP 49 Antibody was produced in mice by repeated immunizations with a recombinant full length human SAP49 expressed in and purified from E. Coli.
Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilut
