ORC2 is one of the six subunits of the ORC (origin recognition complex) that binds origins of replication. The binding of ORC to DNA is ATP-dependent, but so far, specific DNA sequences that define origins of replication have not been identified. The ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. The ORC is regulated in a cell cycle-dependent manner. It is assembled at the end of the anaphase of mitosis and disassembled when cells enter the S phase. Anti-ORC2 Antibody is ideal for research in DNA Replication, Cell Cycle Control and Cancer.
应用类型
Western Blot,
免疫原
Anti-ORC2 Antibody was produced in mice by repeated immunization with human ORC2 (origin recognition complex, subunit 2), using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively.
来源宿主
Mouse
反应性
H. sapiens (Human)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
