KRT7 is a type II keratin of simple nonkeratinizing epithelia. The deduced 489-amino acid protein has a calculated molecular mass of about 54 kD. K7 contains 4 central alpha-helical segments with heptad repeats of hydrophobic residues characteristic of a coiled-coil region. Within this domain, K7 shares 73% homology with epidermal K6B. KRT7 gene contains 9 exons and spans more than 15.6 kb. K7 gene is mapped to chromosome 12. Keratin 7 is expressed in a wide range of epithelial structures in humans. This antibody is suitable for researchers interested in cancer research, cardiovascular diseases, and cytoskeletal signaling research.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Cytokeratin Peptide 7 antibody was produced in mice by repeated immunizations with cytoskeletal preparation of the RT4 human bladder carcinoma cell line.
来源宿主
Mouse
反应性
H. sapiens (Human)
保存建议
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
