- 中文名称
【干冰】Anti-p23 (MOUSE) Monoclonal Antibody - 200-301-G25
- 英文名字
- 【干冰】Anti-p23 (MOUSE) Monoclonal Antibody - 200-301-G25
- 供应商
- Rockland
- 产品货号
- 200-301-G25
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- p23 is a highly conserved ubiquitous protein, known to have an important function as a cochaperone for the hsp90 chaperoning system. Studies have revealed that p23 is a small protein (18 to 25 kDa) with a simple structure. p23 does not have any structuralnhomology with any other known proteins. p23 was first discovered as a part of the Hsp90-progesterone receptor complex along with hsp70, p54 and p50. p23 is a phosphor-protein, which is highly acidic and has an aspartic acid-rich c-terminal domain. Numerous studies have found p23 to be associated with other client proteins like Fes tyrosine kinase, the heme regulated kinase HRI, hsf1 transcription factor, aryl hydrocarbon receptor, telomerase, and Hepadnavirus reverse transcriptase. In spite of several years of study, the exact functional significance of p23 is still not clear. p23 is thought to be involved in the adenosine triphosphate–mediated hsp90 binding of client proteins. Since many hsp90 client proteins are involved in oncogenic survival signaling, a recent study has concluded p23 to be a promising target in leukemic apoptosis. Hsp90 and its co-chaperone p23 are certainly among the emerging anti-tumor targets in oncology.
- 应用类型
- ELISA,Western Blot,
- 免疫原
- p23 Antibody was produced in mice by repeated immunizations raised against a recombinant human full length p23 protein.
- 来源宿主
- Mouse
- 反应性
- Cavia porcellus (Guinea Pig); Gallus gallus (Chicken); H. sapiens (Human); Leporidae (Rabbit); Mus musculus (Mouse); Saccharomyces cerevisiae (Baker's yeast)
- 保存建议
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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