FTO Antibody detects human FTO which is the protein encoded by FTO gene that is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake. Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure. Anti-FTO Antibody is ideal for investigators involved in Neuroscience and Cell Metabolism.
应用类型
IF Microscopy,Western Blot,
免疫原
Anti-FTO Monoclonal Antibody was produced in mouse by repeated immunizations with FTO- Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
来源宿主
Mouse
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.