CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
应用类型
FC (QC tested), IP, IHC(P), WB
免疫原
HPB-ALL human T cell line
来源宿主
小鼠
反应性
Human, Non-human primates
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.