A high affinity agonist of TSPO (Ki = 0.297 nM in rat whole brain) that exhibits IC50 values of 2.73 and 3.04 nM, respectively, against human and rat glial TSPO; produces anxiolytic and antidepressant effects in various animal models, without inducing benzodiazepine-like adverse effects
产品描述
A high affinity agonist of TSPO (Ki = 0.297 nM in rat whole brain) that exhibits IC50 values of 2.73 and 3.04 nM, respectively, against human and rat glial TSPO; produces anxiolytic and antidepressant effects in various animal models, without inducing benzodiazepine-like adverse effects