A 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position; inhibits SUMOylation in vitro (IC50 = 3 µM) and in cells without affecting protein ubiquitination; directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate
产品描述
A 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position; inhibits SUMOylation in vitro (IC50 = 3 µM) and in cells without affecting protein ubiquitination; directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate