A potent, selective inhibitor of Hsp90β (IC50 = 58 nM); inhibits proliferation (GI50s from 53 to 190 nM) or induces cell death in cancer cell lines; orally available and has antitumor effects in human tumor xenografts in mice; increases the sensitivity of tumor cells to ionizing radiation
产品描述
A potent, selective inhibitor of Hsp90β (IC50 = 58 nM); inhibits proliferation (GI50s from 53 to 190 nM) or induces cell death in cancer cell lines; orally available and has antitumor effects in human tumor xenografts in mice; increases the sensitivity of tumor cells to ionizing radiation