Capsiconiate is a coniferyl ester that has been isolated from certain plants in the Solanaceae family, including plants in the genus Capsicum.{29501} It is structurally related to capsaicin (Item No. 92350), the primary heat- and pain-eliciting compound from the Capsicum pepper.{10293} Like capsaicin, capsiconiate is an agonist of the transient receptor potential vanilloid receptor TRPV1 (EC50 = 3.2 µM).{29501} However, the maximum response induced by capsiconiate through TRPV1 is only 20% of that of capsaicin, indicating that it’s a partial agonist of TRPV1.{29501}
产品描述
A coniferyl ester that acts as a partial agonist of TRPV1 (EC50 = 3.2 µM), eliciting only 20% of the maximum response induced by capsaicin
